{"id":4362,"date":"2019-04-09T14:00:55","date_gmt":"2019-04-09T14:00:55","guid":{"rendered":"https:\/\/cusjc.ca\/catalyst\/?post_type=project&#038;p=4362"},"modified":"2019-04-09T18:29:58","modified_gmt":"2019-04-09T18:29:58","slug":"what-happens-in-the-gut-when-we-travel","status":"publish","type":"project","link":"https:\/\/cusjc.ca\/catalyst\/project\/what-happens-in-the-gut-when-we-travel\/","title":{"rendered":"What happens in the gut when we travel?"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_fullwidth_header title=&#8221;What happens in the gut when we travel?&#8221; subhead=&#8221;New traveller&#8217;s diarrhea treatments may be on the horizon as researchers dig into the secrets of the gut microbiome&#8221; header_fullscreen=&#8221;on&#8221; content_orientation=&#8221;bottom&#8221; admin_label=&#8221;Fullwidth Header&#8221; _builder_version=&#8221;3.21&#8243; background_image=&#8221;https:\/\/cusjc.ca\/catalyst\/wp-content\/uploads\/2019\/04\/Resize-for-web.jpg.jpeg&#8221; title_font_size=&#8221;50px&#8221; title_text_shadow_style=&#8221;preset1&#8243; subhead_text_shadow_style=&#8221;preset1&#8243; title_font=&#8221;||||||||&#8221; subhead_font=&#8221;||||||||&#8221; subhead_font_size=&#8221;24px&#8221;]<\/p>\n<p><strong>\u00a0<\/strong><\/p>\n<p><strong>By Jordana Colomby and Matt Gergyek<\/strong><\/p>\n<p>[\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;0|0px|14px|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;22.0156px|0px|0|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text admin_label=&#8221;Story copy&#8221; _builder_version=&#8221;3.21&#8243; text_font=&#8221;||||||||&#8221;]<\/p>\n<p><span style=\"font-weight: 400;\">Looking back on it now, Erin Hynes laughs about her and her partner\u2019s bouts of <g class=\"gr_ gr_26 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"26\" data-gr-id=\"26\">traveller\u2019s<\/g> diarrhea while they were on their nine-month trip through Asia and Europe. But at the time, there was nothing funny about it.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Hynes said she remembers being on a bus in Laos, a country in Southeast Asia, at the beginning of their trip. En route to Kuang Si, a famous waterfall just outside of Luang Prabang, the bus was weaving along a bumpy road, so the two were a bit queasy <g class=\"gr_ gr_22 gr-alert gr_gramm gr_inline_cards gr_run_anim Punctuation only-ins replaceWithoutSep\" id=\"22\" data-gr-id=\"22\">to<\/g> begin with. But Hynes\u2019s partner turned to her with a familiar look in his eyes.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cI don\u2019t feel very good,\u201d he said, and Hynes said she instantly knew what was about to happen.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">For four weeks, Hynes and her partner took turns battling\u00a0<span><g class=\"gr_ gr_26 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"26\" data-gr-id=\"26\">traveller\u2019s<\/g> diarrhea<\/span>, which is common for many people with wanderlust: Around 60 <g class=\"gr_ gr_24 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"24\" data-gr-id=\"24\">per cent<\/g> of <g class=\"gr_ gr_25 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"25\" data-gr-id=\"25\">travellers<\/g> going from industrialized to developing countries get some form of\u00a0<span><g class=\"gr_ gr_26 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"26\" data-gr-id=\"26\">traveller\u2019s<\/g> diarrhea<\/span>, according to a<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4615231\/\"> <span style=\"font-weight: 400;\">2015 study published in the journal <\/span><span style=\"font-weight: 400;\">Gut Microbes<\/span><\/a><span style=\"font-weight: 400;\">.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">There\u2019s not one specific cause of\u00a0<span><g class=\"gr_ gr_26 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"26\" data-gr-id=\"26\">traveller\u2019s<\/g> diarrhea<\/span>; it\u2019s an umbrella term for many different illnesses caused by a wide range of bacteria, viruses <g class=\"gr_ gr_27 gr-alert gr_gramm gr_inline_cards gr_run_anim Punctuation only-ins replaceWithoutSep\" id=\"27\" data-gr-id=\"27\">and<\/g> parasites that result in frequent, loose, or watery stool, along with stomach pains, vomiting, and fevers. Although\u00a0<span><g class=\"gr_ gr_26 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"26\" data-gr-id=\"26\">traveller\u2019s<\/g> diarrhea<\/span> might seem like nothing more than a few trips to the toilet, the long term impacts can be detrimental to one\u2019s gut health. Researchers are taking advantage of the burgeoning field of microbiome research to search for new ways to prevent and treat\u00a0<span><g class=\"gr_ gr_26 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"26\" data-gr-id=\"26\">traveller\u2019s<\/g> diarrhea<\/span>\u00a0\u2014 giving hope to <g class=\"gr_ gr_54 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"54\" data-gr-id=\"54\">travellers<\/g> prone to miserable guts.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u00a0<span>The inner workings of the gut microbiome \u2014 the collection of bacteria living in your intestines \u2014 are extremely complex. These resident microorganisms help humans digest food and fight pathogens. Bacteria hitchhiking on food and drink constantly enter and leave the gut microbiome. T<\/span><g class=\"gr_ gr_15 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"15\" data-gr-id=\"15\">ravelling<\/g><span> can disrupt a person&#8217;s generally stable microbiome, which can spell trouble on the toilet. When pathogens that commonly cause\u00a0<\/span><g class=\"gr_ gr_26 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"26\" data-gr-id=\"26\">traveller\u2019s<\/g><span> diarrhea, such as <\/span>enterotoxigenic<i> Escherichia coli <\/i><span>(ETEC) or bacteria of the Campylobacter genus, get into the gut, a case of diarrhea could strike.<\/span><\/span><\/p>\n<p><span style=\"font-weight: 400;\"><\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_code _builder_version=&#8221;3.21&#8243;]<\/p>\n<div class=\"infogram-embed\" data-id=\"f54a4844-84b4-441e-9677-b6040bb0c56d\" data-type=\"interactive\" data-title=\"Common causes of traveller's diarrhea (TD)\"><\/div>\n<p><script>!function(e,t,s,i){var n=\"InfogramEmbeds\",o=e.getElementsByTagName(\"script\")[0],d=\/^http:\/.test(e.location)?\"http:\":\"https:\";if(\/^\\\/{2}\/.test(i)&&(i=d+i),window[n]&&window[n].initialized)window[n].process&&window[n].process();else if(!e.getElementById(s)){var r=e.createElement(\"script\");r.async=1,r.id=s,r.src=i,o.parentNode.insertBefore(r,o)}}(document,0,\"infogram-async\",\"https:\/\/e.infogram.com\/js\/dist\/embed-loader-min.js\");<\/script><\/p>\n<div style=\"padding:8px 0;font-family:Arial!important;font-size:13px!important;line-height:15px!important;text-align:center;border-top:1px solid #dadada;margin:0 30px\"><a href=\"https:\/\/infogram.com\/f54a4844-84b4-441e-9677-b6040bb0c56d\" style=\"color:#989898!important;text-decoration:none!important;\" target=\"_blank\" rel=\"noopener noreferrer\">Common causes of traveller&#8217;s diarrhea (TD)<\/a><br \/><a href=\"https:\/\/infogram.com\" style=\"color:#989898!important;text-decoration:none!important;\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Infogram<\/a><\/div>\n<p>[\/et_pb_code][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;0|0px|44.0312px|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;5px|0px|3px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_image src=&#8221;https:\/\/cusjc.ca\/catalyst\/wp-content\/uploads\/2019\/04\/Escherichia_coli_resize-for-web.jpg.jpeg&#8221; _builder_version=&#8221;3.21&#8243;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding=&#8221;0|0px|0|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text _builder_version=&#8221;3.21&#8243;]<\/p>\n<p><span style=\"font-weight: 400;\">Escherichia coli,<\/span><i><span style=\"font-weight: 400;\"> the main culprit for <g class=\"gr_ gr_9 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"9\" data-gr-id=\"9\">traveller\u2019s<\/g> diarrhea, seen under a scanning electron microscope. [Photo courtesy of Wikicommons, CDC Evangeline Sowers &amp; Janice Carr].<\/span><\/i><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;0|0px|0|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;0|0px|22.0156px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text _builder_version=&#8221;3.21&#8243;]<\/p>\n<p>\u00a0<span style=\"font-size: 14px;\">Currently, the front line of protection against <g class=\"gr_ gr_29 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"29\" data-gr-id=\"29\">traveller\u2019s<\/g> diarrhea is a temporary oral vaccine called Dukarol. It\u2019s the only vaccine used for <g class=\"gr_ gr_30 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"30\" data-gr-id=\"30\">traveller\u2019s<\/g> diarrhea prevention that is available in Canada and it was first introduced to the public in October of 2001, according to a 2014 article published in the<\/span><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC4144262\/\" style=\"font-size: 14px;\"> <i>Therapeutic Advances in Vaccines<\/i><\/a><span style=\"font-size: 14px;\"> journal.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But Dukarol isn\u2019t technically a <g class=\"gr_ gr_26 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"26\" data-gr-id=\"26\">traveller\u2019s<\/g> diarrhea vaccine, it\u2019s a vaccine designed to protect against cholera \u2014 an infectious disease that causes severe watery diarrhea and can lead to dehydration and death if left untreated, according to Navy Capt. Mark Riddle. He\u2019s a professor and chair of preventive medicine and biostatistics at the Uniformed Services University of the Health Sciences in Bethesda, but to his kids, he\u2019s Dr. Diarrhea.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Dukarol introduces minute amounts of inactive cholera bacteria into the patient, forcing their body to produce protective antibodies. Since the toxins produced by cholera are about 98 <g class=\"gr_ gr_27 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"27\" data-gr-id=\"27\">per cent<\/g> similar to a do-called \u201cheat-labile toxin\u201d that ETEC produces, \u201ctheoretically, you get vaccinated for cholera that has this toxin component in it, you develop an immune response to that, and that protects you from the ETEC,\u201d Riddle explained.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But in reality, that isn\u2019t exactly what happens.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">ETEC strains that produce this heat-labile toxin accounts for less than 10 <g class=\"gr_ gr_31 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"31\" data-gr-id=\"31\">per cent<\/g> of all causes of diarrhea. \u201cSo, hypothetically, if the vaccine is 60 <g class=\"gr_ gr_32 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"32\" data-gr-id=\"32\">per cent<\/g> effective against [heat labile]-producing ETEC, and only one out of 10 <g class=\"gr_ gr_33 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"33\" data-gr-id=\"33\">traveller\u2019s<\/g> diarrhea episodes are caused by [heat labile] ETEC, then such hypothetical vaccine is only going to work to prevent about six out of 100 episodes of [traveller\u2019s diarrhea],\u201d Riddle said, \u201cso the chances of a Dukarol working for your <g class=\"gr_ gr_34 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"34\" data-gr-id=\"34\">traveller\u2019s<\/g> diarrhea are relatively small.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Although Dukarol isn\u2019t actually a defence against traveller\u2019s diarrhea, it\u2019s the closest thing travellers have to a vaccine. Riddle is one of the researchers working on developing a vaccine specific for traveller\u2019s diarrhea, but it hasn\u2019t been easy. \u201cThe [vaccines] we\u2019ve been working on for the past 15 years have not come to fruition yet. But we\u2019re getting smarter,\u201d Riddle said. <\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_code _builder_version=&#8221;3.21&#8243;]<\/p>\n<div class=\"infogram-embed\" data-id=\"139ea5b0-37b4-4db6-8790-98ba7b2e1cee\" data-type=\"interactive\" data-title=\"Caplylobactor\"><\/div>\n<p><script>!function(e,t,s,i){var n=\"InfogramEmbeds\",o=e.getElementsByTagName(\"script\")[0],d=\/^http:\/.test(e.location)?\"http:\":\"https:\";if(\/^\\\/{2}\/.test(i)&&(i=d+i),window[n]&&window[n].initialized)window[n].process&&window[n].process();else if(!e.getElementById(s)){var r=e.createElement(\"script\");r.async=1,r.id=s,r.src=i,o.parentNode.insertBefore(r,o)}}(document,0,\"infogram-async\",\"https:\/\/e.infogram.com\/js\/dist\/embed-loader-min.js\");<\/script><\/p>\n<div style=\"padding:8px 0;font-family:Arial!important;font-size:13px!important;line-height:15px!important;text-align:center;border-top:1px solid #dadada;margin:0 30px\"><a href=\"https:\/\/infogram.com\/139ea5b0-37b4-4db6-8790-98ba7b2e1cee\" style=\"color:#989898!important;text-decoration:none!important;\" target=\"_blank\" rel=\"noopener noreferrer\">Caplylobactor<\/a><br \/><a href=\"https:\/\/infogram.com\" style=\"color:#989898!important;text-decoration:none!important;\" target=\"_blank\" rel=\"nofollow noopener noreferrer\">Infogram<\/a><\/div>\n<p>[\/et_pb_code][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;0|0px|5px|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;2px|0px|22.0156px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text _builder_version=&#8221;3.21&#8243; header_font=&#8221;||||||||&#8221; header_3_font=&#8221;||||||||&#8221; header_3_text_color=&#8221;#d37400&#8243;]<\/p>\n<h3><span style=\"font-weight: 400;\">Fighting the travel bug<\/span><\/h3>\n<p><span style=\"font-weight: 400;\">Beatrix Morrallee is a nurse manager with<\/span><a href=\"https:\/\/www.passporthealthglobal.com\/ca\/\"> <span style=\"font-weight: 400;\">Passport Health<\/span><\/a><span style=\"font-weight: 400;\">, a private travel health company with over 270 travel clinics across North America.<\/span><\/p>\n<p><span>Morrallee said from her experience over 50 <g class=\"gr_ gr_13 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"13\" data-gr-id=\"13\">per cent<\/g> of patients at Passport Health choose to take the Dukarol vaccine.<\/span><\/p>\n<p><span>\u201cWe talk to every person about [Dukarol], but we tell them it doesn\u2019t make them superhuman,\u201d said Morrallee, who oversees all of the Passport Health\u2019s 19 locations in Ontario. \u201cOur job is to give [clients] all the options so they can make an informed [consensual decision] on what they want and what they can afford.\u201d<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;3.21&#8243;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;0|0px|4px|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;23.3906px|0px|1px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_image src=&#8221;https:\/\/cusjc.ca\/catalyst\/wp-content\/uploads\/2019\/04\/Passport-Health-resize.jpg.jpeg&#8221; _builder_version=&#8221;3.21&#8243;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding=&#8221;0|0px|22.0156px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text _builder_version=&#8221;3.21&#8243;]<\/p>\n<p><i><span style=\"font-weight: 400;\">Passport Health has two locations in Ottawa. The one pictured here is downtown on Albert Street. [Photo \u00a9 Matt Gergyek].<\/span><\/i><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;0|0px|3px|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;6px|0px|0|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text _builder_version=&#8221;3.21&#8243;]<\/p>\n<p><span style=\"font-size: 14px;\">Hynes took Dukarol but it didn\u2019t stop the 29-year-old creator of<\/span><a href=\"https:\/\/www.pinatravels.org\/\" style=\"font-size: 14px;\"> Pina Travels<\/a><span style=\"font-size: 14px;\">, a travel site focused on budgeting and itineraries, from falling ill again and again.\u00a0<\/span><span style=\"font-weight: 400;\"><\/span><\/p>\n<p><span>\u201cI was on a bit of a streak,\u201d Hynes said. She hadn\u2019t gotten ill for about a month and said she was feeling great when she arrived in Nepal \u2014 her second-last destination before returning home to Toronto. Hynes said she remembers hearing people in her hostel warn each other not to drink the free bottled water, but unfortunately, she had already made that mistake.<\/span><\/p>\n<p><span>Over the next four days in Edinburgh, Hynes lost control of her bowels and found herself constantly darting to the washroom only to realize it was too late. <\/span><span>\u201cIt was awful,\u201d she said.<\/span><\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;3.21&#8243;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;0|0px|31px|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;23.3906px|0px|3px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_image src=&#8221;https:\/\/cusjc.ca\/catalyst\/wp-content\/uploads\/2019\/04\/Laos-Resized-for-Web.jpg.jpeg&#8221; _builder_version=&#8221;3.21&#8243;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding=&#8221;0|0px|3px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text _builder_version=&#8221;3.21&#8243;]<\/p>\n<p><i><span style=\"font-weight: 400;\">A photo from Hynes\u2019s journey taken in Laos, a country in Southeast Asia. [Photo courtesy of Erin Hynes].<\/span><\/i><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;0|0px|0|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;3px|0px|23.3906px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text _builder_version=&#8221;3.21&#8243;]<\/p>\n<p><span style=\"font-weight: 400;\">Morrallee said Passport Health recommends medications such as Imodium or Pepto Bismol for the first regimen of\u00a0traveller&#8217;s diarrhea\u00a0treatment and antibiotics when these treatments don\u2019t work.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">But antibiotics, if overused, can have a major downside: the global spread of antibiotic resistance.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">\u201cWe\u2019re in a losing battle against bacteria,\u201d Riddle said. \u201cIt\u2019s a tough battle and we continue to develop antibiotics to try to treat infections appropriately, so resistance does develop.\u201d<\/span><\/p>\n<p><span style=\"font-weight: 400;\">As antibiotic resistance develops and spreads across the world, our medications become powerless and once-treatable illnesses can become fatal. Riddle said there are many ways drug-resistant bacteria can travel across country lines, like food imports and bird migration, but travellers can be vectors as well.<\/span><span style=\"font-size: 14px;\">\u00a0<\/span><\/p>\n<p><span style=\"font-weight: 400;\">One of the controversies in the field right now is whether to take antibiotics for minor cases of\u00a0traveller&#8217;s diarrhea\u00a0or whether it\u2019s best for patients to just ride out the symptoms and heal on their own. Minimal intervention has its own risks: Untreated, infected people might spread the pathogen to others and they are also at risk of developing chronic health problems connected to certain infections.<\/span><\/p>\n<p><span style=\"font-weight: 400;\">Campylobacter, one of the top three causes of\u00a0traveller&#8217;s diarrhea, can lead to issues such as arthritis, irritable bowel syndrome (IBS), or Guillain-Barr\u00e9 syndrome, which is an acute flash of paralysis, according to Riddle.<\/span><\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;3.21&#8243;][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;1px|0px|4px|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;23.3906px|0px|6px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_image src=&#8221;https:\/\/cusjc.ca\/catalyst\/wp-content\/uploads\/2019\/04\/Camplyobacter_resize.jpg.jpeg&#8221; _builder_version=&#8221;3.21&#8243;][\/et_pb_image][\/et_pb_column][\/et_pb_row][et_pb_row custom_padding=&#8221;2px|0px|23.3906px|0px|false|false&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;4_4&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text _builder_version=&#8221;3.21&#8243;]<\/p>\n<p><em>Bacteria of the Campylobacter genus, which causes about 15 <g class=\"gr_ gr_8 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"8\" data-gr-id=\"8\">per cent<\/g> of <g class=\"gr_ gr_9 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"9\" data-gr-id=\"9\">traveller\u2019s<\/g> diarrhea cases, according to one count, pictured here under a scanning electron microscope. [Photo courtesy of Wikicommons, Janice Carr, CDC\/ Patricia Fields &amp; Collette Fitzgerald].<\/em><\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;1px|0px|46.7969px|0px|false|false&#8221;][et_pb_row _builder_version=&#8221;3.21&#8243;][et_pb_column type=&#8221;3_5&#8243; _builder_version=&#8221;3.21&#8243;][et_pb_text _builder_version=&#8221;3.21&#8243;]<\/p>\n<p>Riddle said these \u201cpost-infectious cases [usually go] away in about six to 12 months, but in a certain percentage, say 30 to 40 <g class=\"gr_ gr_33 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"33\" data-gr-id=\"33\">per cent<\/g>, it\u2019s still there five years [later].\u201d<\/p>\n<p>While post-infectious diseases are a concern, most people\u2019s microbiomes bounce back when they return home. Some people won\u2019t even experience traveller&#8217;s diarrhea at all.<\/p>\n<p>The gut microbiome inevitably changes with travel. Getting on a plane, <g class=\"gr_ gr_32 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"32\" data-gr-id=\"32\">travelling<\/g> to a new city, and eating different food all impact the microbial inhabitants of your gut. However, that doesn\u2019t mean a <g class=\"gr_ gr_34 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"34\" data-gr-id=\"34\">traveller<\/g> is guaranteed to get sick.<\/p>\n<p>\u201cYou can have a change and actually have no illness, you could have <g class=\"gr_ gr_44 gr-alert gr_gramm gr_inline_cards gr_run_anim Grammar multiReplace\" id=\"44\" data-gr-id=\"44\">change<\/g> and have an illness,\u201d explained Dave Rasko, a professor at the University of Maryland School of Medicine. \u201cIn two people that change could be relatively similar, and yet the outcomes could be entirely different.\u201d<\/p>\n<p>Whether or not you get sick depends not only on the pathogens introduced to your body but also on your initial microbiome, according to Dr. Brett Finlay, a professor of microbiology at the University of British Columbia (UBC).\u00a0<\/p>\n<p>Riddle found that approximately 15 to 20 <g class=\"gr_ gr_41 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"41\" data-gr-id=\"41\">per cent<\/g> of people always <g class=\"gr_ gr_40 gr-alert gr_gramm gr_inline_cards gr_run_anim Grammar multiReplace\" id=\"40\" data-gr-id=\"40\">gets<\/g> sick, and another 15 to 20 <g class=\"gr_ gr_42 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"42\" data-gr-id=\"42\">per cent<\/g> never do.<\/p>\n<p>\u201cIt\u2019s a bell-shaped curve,\u201d Riddle said.\u201d You have people that are on the extreme of being more susceptible and [others who are] naturally protected.\u201d<\/p>\n<p>Even though we know some people are less susceptible to developing traveller&#8217;s diarrhea, researchers are just at the beginning of being able to translate that knowledge into treatments. At the moment, researchers are focused on understanding the basic <g class=\"gr_ gr_37 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling\" id=\"37\" data-gr-id=\"37\">composition<\/g> of different people\u2019s microbiome, which they do by analyzing their fecal samples to see what different microorganisms live there.<\/p>\n<p>For example, scientists have been able to determine that some people\u2019s microbiomes are better at fighting off and recovering from pathogens than others. They have started doing fecal transplants \u2014 transplanting the gut microbiomes found in poop from healthy individuals <g class=\"gr_ gr_39 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"39\" data-gr-id=\"39\">to<\/g> sick ones \u2014 to successfully treating some serious cases of traveller&#8217;s diarrhea.<\/p>\n<p>Once researchers better understand the microbiome, they\u2019ll be more adept at manipulating it to help prevent and cure traveller&#8217;s diarrhea \u2014 giving hope to <g class=\"gr_ gr_43 gr-alert gr_spell gr_inline_cards gr_run_anim ContextualSpelling multiReplace\" id=\"43\" data-gr-id=\"43\">traveller\u2019s<\/g> who don\u2019t want to flush their vacation plans down the toilet along with their lunch.<\/p>\n<p>&nbsp;<\/p>\n<p>[\/et_pb_text][\/et_pb_column][et_pb_column type=&#8221;2_5&#8243; _builder_version=&#8221;3.21&#8243;][\/et_pb_column][\/et_pb_row][\/et_pb_section]<\/p>\n","protected":false},"excerpt":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; fullwidth=&#8221;on&#8221; _builder_version=&#8221;3.21&#8243;][et_pb_fullwidth_header title=&#8221;What happens in the gut when we travel?&#8221; subhead=&#8221;New traveller&#8217;s diarrhea treatments may be on the horizon as researchers dig into the secrets of the gut microbiome&#8221; header_fullscreen=&#8221;on&#8221; content_orientation=&#8221;bottom&#8221; admin_label=&#8221;Fullwidth Header&#8221; _builder_version=&#8221;3.21&#8243; background_image=&#8221;https:\/\/cusjc.ca\/catalyst\/wp-content\/uploads\/2019\/04\/Resize-for-web.jpg.jpeg&#8221; title_font_size=&#8221;50px&#8221; title_text_shadow_style=&#8221;preset1&#8243; subhead_text_shadow_style=&#8221;preset1&#8243; title_font=&#8221;||||||||&#8221; subhead_font=&#8221;||||||||&#8221; subhead_font_size=&#8221;24px&#8221;] \u00a0 By Jordana Colomby and Matt Gergyek [\/et_pb_fullwidth_header][\/et_pb_section][et_pb_section fb_built=&#8221;1&#8243; _builder_version=&#8221;3.21&#8243; custom_padding=&#8221;0|0px|14px|0px|false|false&#8221;][et_pb_row custom_padding=&#8221;22.0156px|0px|0|0px|false|false&#8221; [&hellip;]<\/p>\n","protected":false},"author":70,"featured_media":4438,"comment_status":"open","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"","_et_gb_content_width":"","footnotes":""},"project_category":[135],"project_tag":[150,154,153,148,147,146,143,141,142,140,137,149,138,139,151,152,144,145,136,55],"class_list":["post-4362","project","type-project","status-publish","has-post-thumbnail","hentry","project_category-feature","project_tag-beatrix-morrallee","project_tag-brett-finlay","project_tag-dave-rasko","project_tag-dukarol","project_tag-e-coli","project_tag-erin-hynes","project_tag-fecal-transplants","project_tag-gut","project_tag-gut-health","project_tag-gut-microbiome","project_tag-jordana-colomby","project_tag-mark-riddle","project_tag-matt-gergyek","project_tag-microbiome","project_tag-passport-health","project_tag-pina-travels","project_tag-travel","project_tag-travel-health","project_tag-travellers-diarrhea","project_tag-vaccine"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v18.3 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>What happens in the gut when we travel? 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